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LSM4243 

TUMOUR BIOLOGY
   2018/2019, Semester 2
   Yong Loo Lin School of Medicine (Physiology)
Modular Credits: 4
  Tags: --

Prerequisites

TopLSM2103

Learning Outcomes

Top

Lecture Topics

Lecturer
L1 Apoptosis – Pathways and Detection Techniques R Taneja
L2

Regulators of apoptosis –I

R Taneja
L3

Regulators of apoptosis -II

R Taneja
T1

Tutorial 1

R Taneja
T2

Tutorial 2

R Taneja
L4

Cancer stem cells (CSC) -I

D Ong 
L5 CSC -II D Ong
L6

Role of tumour microenvironment on CSC plasticity

D Ong
L7 CSC and therapy resistance D Ong
T3 Tutorial 1 D Ong
T4 Tutorial 2 D Ong
L8 Process of tumorigenesis Shen HM
L9

Autophagy in tumour biology

Shen HM
T5 Tutorial 1 Shen HM
T6 Tutorial 2 Shen HM
L10 Mechanobiology in cancer M Sudol
L11

DNA repair and Cancer

P Hande
L12

Telomeres, Telomerase and Cancer

P Hande
T7

Tutorial 1

P Hande
T8

Tutorial 2

P Hande
L14

Metastasis

ASG Lee

TEXT BOOKS (Main References): Selected Research Articles

BASIC SUPPLEMENTARY READINGS
:

Robert A Weinberg 2013 The Biology of Cancer (GarlandScience), Second Edition, ISBN-10: 0815342209 ISBN:-13978-0815342205

 

Teaching Modes

TopThis module will be taught in two modes: lecture and tutorial/CA. For CA, an assignment will be given by the lecturer a report will need to be submitted to the lecturer by the assigned date.  The format for the report will be given in due course.

Schedule

Top

TIMETABLE FOR SEMESTER II, 2018/2019
LSM4243 – TUMOUR BIOLOGY
Module Coordinators
A/P Reshma Taneja (phsrt@nus.edu.sg)
Dr. Derrick Ong  (phsostd@nus.edu.sg)

 
LECTURES:
 
TUESDAYS & THURSDAY
   
TIME: 10am - 12pm (Tue); 2 - 4pm (Thurs)    
VENUE: LT21 (Tue); LT29 (Thurs)    
Week Day Date

Lecture Topics

Lecturer  
1 Tues 15 Jan L1 Apoptosis – Pathways and Detection Techniques R Taneja  
  Thurs 17 Jan L2

Regulators of apoptosis –I

R Taneja  
2 Tues 22 Jan L3

Regulators of apoptosis -II

R Taneja  
  Thurs 24 Jan T1

Tutorial 1

R Taneja  
3 Tues 29 Jan T2

Tutorial 2

R Taneja  
  Thurs 31 Jan L4

Cancer stem cells (CSC) -I

D Ong   
4 Tues 5 Feb  

PUBLIC HOLIDAY (CHINESE NEW YEAR)

   
  Thurs 7 Feb L5 CSC -II D Ong  
5 Tues 12 Feb L6

Role of tumour microenvironment on CSC plasticity

D Ong  
  Thurs 14 Feb L7 CSC and therapy resistance D Ong  
6 Tues 19 Feb T3 Tutorial 1 D Ong  
  Thurs 21 Feb T4 Tutorial 2 D Ong  
        RECESS WEEK (FEB 23-MARCH 3)    
7 Tues 5 Mar L8 Process of tumorigenesis Shen HM  
  Thurs 7 Mar L9

Autophagy in tumour biology

Shen HM  
8 Tues 12 Mar T5 Tutorial 1 Shen HM  
  Thurs 14 Mar T6 Tutorial 2 Shen HM  
9 Tues 19 Mar L10 Mechanobiology in cancer M Sudol  
  Thurs 21 Mar L11

DNA repair and Cancer

P Hande  
10 Tues 26 Mar L12

Telomeres, Telomerase and Cancer

P Hande  
  Thurs 28 Mar T7

Tutorial 1

P Hande  
11 Tues 2 Apr T8

Tutorial 2

P Hande  
  Thurs 4 Apr L14

Metastasis

ASG Lee  
12 Tues 9 Apr  

GUEST LECTURE:

Dr. Anand Jeyasekharan (CSI)  
  Thurs 11 Apr  

Revision

   
13 Tue 16 Apr  

MCQ Test

   
  Thurs 18 Apr  

Revision

   
     

READING WEEK: Sat 20 Apr to Fri 26 Apr 2019

   
     

FINAL EXAMINATION:  Saturday, 27 April 2019, 9 am

   
     

Vacation: Sun, 12 May – Sun, 04 Aug 2019 (12 weeks)

   

 
Lecturers:
A/Prof Reshma Taneja
Dr. Derrick Ong
Prof Shen Han-Ming
A/P Marius Sudol
A/P Prakash Hande
Dr Ann Lee

Syllabus

Top

 

 

 

Practical Work

TopThere is no practical work for this module.

Assessment

Top

 The module will be assessed by the following two methods:
(1) CA report and MCQ Test (40%)
(2) Final examination (closed book) (60%): MEQ

 

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