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LSM3223 

IMMUNOLOGY
   2014/2015, Semester 2
   Yong Loo Lin School of Medicine (Microbiology & Immunology)
Modular Credits: 4
  Tags: --

Learning Outcomes

TopThis course provides the central concepts of immunology and the foundation for understanding how immunity functions. The subjects of innate immunity and haematopoiesis introduce the origin and role of different cell types in immunity. The mechanics of how the body protects itself from disease are explored in relation to T and B cell biology, monoclonal antibodies, cytokines, major histocompatibility complex and antigen presentation. Other topics include hypersensitivity, immunodeficiencies, tolerance, autoimmunity, resistance and immunization to infectious diseases.

Prerequisites

TopLSM2103

Schedule

TopTIMETABLE FOR SEMESTER II, 2014/2015
 
LSM3223-IMMUNOLOGY
Module Coordinator: Dr Zhang Yongliang
Email: miczy@nus.edu.sg
Tel: 6516-6407
 
 
LECTURES:
 
MONDAYS
PRACTICALS /
TUTORIALS:
THURSDAYS (EVEN WEEKS)
TIME: 1000 – 1200 hrs TIME: 1200 – 1800 hrs
VENUE: LT34 VENUE: LS LAB 9 MD4 LEVEL 4
 
 
*Practical alternate with LSM3232 and LSM3221 (ODD WEEKS)
 

WK

MONTH

LECTURES
MONDAYS
PRACTICALS
THURSDAYS (EVEN WEEKS)
  1.  
Jan 12 Overview of immunology
     Cells and structures of the immune   
     system
15
  1.  
  19 Innate immunity I
    Innate immunity II
22* Immunoglobulin structure and 
       function and B cell development
       Antibody-antigen interactions (12-
       2pm)
  1.  
  26 Complement
     Cytokines and chemokines
29
  1.  
Feb 2 Major Histocompatibility Complex
   Antigen Processing/Presentation
 
5* Practical 1: Cells of the immune system plus antigens and antibodies
Tutorial 1: Innate immunity, humoral immunity & effector mechanisms
  1.  
  9 Generation of immunoglobulin and T  
   cell receptor diversity
   Experimental Immunology
 
12
  1.  
  16 T cell development and activation
    Cell-mediated immunity
 
19*                  Public Holiday
Recess week : Sat 21 Feb – Sun 1 Mar 2015  (1 week)
  1.  
Mar 2 Infection & immunity: viruses & 
   parasites            
5
  1.  
  9    eLearning Week 12                eLearning Week
 
  1.  
  16 Continuous assessment (lecture topics 1-12) (10 .30 – 11.30 am, venue: ?)  19
  1.  
  23 Infection and immunity: bacteria
     &fungi 
     Vaccine & immunization
 
26*Practical 2: Cell-mediated immunity: ELISpot, flow cytometry, lymphocyte proliferation, cytotoxicity assays
  1.  
Mar/Apr 30 Immunological tolerance     
     Autoimmunity
 
2
  1.  
Apr 6 Hypersensitivity 
      Immunodeficiency
 
9* Practical 3: Enzyme-linked immunosorbent assay and immunoblot
  1.  
  13 Tumour immunology
   Module summary/discussion 
16
READING PERIOD : Sat 18 Apr to Fri 24 Apr 2015 (1 week)
EXAMINATION :  Wed, 29 Apr 2015, 1:00 P.M.
VACATION : Sun 10 May 2015 to Sun 2 Aug 2015 (12 weeks)
 
Textbook:
 
Cellular and Molecular Immunology, 7th edition (Authors: Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai), ELSEVIER
 

Workload

Top2-0.5-3-2-4

Workload Components : A-B-C-D-E
A: no. of lecture hours per week
B: no. of tutorial hours per week
C: no. of lab hours per week
D: no. of hours for projects, assignments, fieldwork etc per week
E: no. of hours for preparatory work by a student per week

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