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Timetable
LSM3223
IMMUNOLOGY
2014/2015, Semester 2
Yong Loo Lin School of Medicine (Microbiology & Immunology)
Modular Credits: 4
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Learning Outcomes
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This course provides the central concepts of immunology and the foundation for understanding how immunity functions. The subjects of innate immunity and haematopoiesis introduce the origin and role of different cell types in immunity. The mechanics of how the body protects itself from disease are explored in relation to T and B cell biology, monoclonal antibodies, cytokines, major histocompatibility complex and antigen presentation. Other topics include hypersensitivity, immunodeficiencies, tolerance, autoimmunity, resistance and immunization to infectious diseases.
Prerequisites
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LSM2103
Schedule
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TIMETABLE FOR SEMESTER II, 2014/2015
LSM3223-IMMUNOLOGY
Module Coordinator: Dr Zhang Yongliang
Email:
miczy@nus.edu.sg
Tel: 6516-6407
LECTURES:
MONDAYS
PRACTICALS /
TUTORIALS:
THURSDAYS (EVEN WEEKS)
TIME:
1000 – 1200 hrs
TIME:
1200 – 1800 hrs
VENUE:
LT34
VENUE:
LS LAB 9 MD4 LEVEL 4
*Practical alternate with LSM3232 and LSM3221 (ODD WEEKS)
WK
MONTH
LECTURES
MONDAYS
PRACTICALS
THURSDAYS (EVEN WEEKS)
Jan
12 Overview of immunology
Cells and structures of the immune
system
15
19 Innate immunity I
Innate immunity II
22* Immunoglobulin structure and
function and B cell development
Antibody-antigen interactions (12-
2pm)
26 Complement
Cytokines and chemokines
29
Feb
2 Major Histocompatibility Complex
Antigen Processing/Presentation
5*
Practical 1
:
Cells of the immune system plus antigens and antibodies
Tutorial 1
: Innate immunity, humoral immunity & effector mechanisms
9 Generation of immunoglobulin and T
cell receptor diversity
Experimental Immunology
12
16 T cell development and activation
Cell-mediated immunity
19* Public Holiday
Recess week :
Sat 21 Feb – Sun 1 Mar 20
15
(1 week)
Mar
2 Infection & immunity: viruses &
parasites
5
9 eLearning Week
12 eLearning Week
16
Continuous assessment (lecture topics 1-12)
(10 .30 – 11.30 am, venue: ?)
19
23 Infection and immunity: bacteria
&fungi
Vaccine & immunization
26*
Practical 2:
Cell-mediated immunity: ELISpot, flow cytometry, lymphocyte proliferation, cytotoxicity assays
Mar/Apr
30 Immunological tolerance
Autoimmunity
2
Apr
6 Hypersensitivity
Immunodeficiency
9*
Practical 3:
Enzyme-linked immunosorbent assay and immunoblot
13 Tumour immunology
Module summary/discussion
16
READING PERIOD : Sat 18
Apr to Fri
24
Apr 20
15
(1 week)
EXAMINATION :
Wed
,
29
Apr 20
15
,
1:00 P.M.
VACATION : Sun 10 May 20
15
to Sun
2
Aug 2015 (12 weeks)
Textbook:
Cellular and Molecular Immunology, 7
th
edition
(Authors: Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai), ELSEVIER
Workload
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2-0.5-3-2-4
Workload Components : A-B-C-D-E
A: no. of lecture hours per week
B: no. of tutorial hours per week
C: no. of lab hours per week
D: no. of hours for projects, assignments, fieldwork etc per week
E: no. of hours for preparatory work by a student per week