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Learning Outcomes

TopAn advanced course in the study of infectious diseases of man with emphasis on new and emerging infections as well as those of major clinical/economic importance. Core topics include understanding the principles and practice of Medical Microbiology, the nature and emergence of antimicrobial resistance, changing epidemiology of infections and laboratory diagnosis using classical diagnostic techniques and current molecular approaches. Seminars will be conducted as team presentations to explore current topics on infectious diseases in depth. A strong practical component is included.

Prerequisites

TopFor Life Sciences major. Students must pass LSM3232 or LSM3225.

Schedule

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TIMETABLE FOR SEMESTER II, 2008/2009

LSM4223 – MEDICAL MICROBIOLOGY

Module Coordinators: Dr Kevin Tan/ A/P Vincent Chow

Email: mictank@nus.edu.sg

Tel: 6516-6780

LECTURES:	WEDNESDAYS	PRACTICALS:	FRIDAYS
TIME:	1400 – 1600 hrs	TIME:	1000 – 1400 hrs
VENUE:	LT20	VENUE:	LS Lab 9 MD4 Level 4

WK	MONTH	LECTURES	PRACTICALS
WK	MONTH	WEDNESDAYS	FRIDAYS
1.	Jan	14 Introduction (KT)	16 *
2.		21 Lab Methods (GK)	23 P1 (Diagnostic Microbiology) (SA/GK)
3.		28 Microbial Pathogenesis (SP)	30 P2 (Diagnostic Microbiology) (SA/GK)
4.	Feb	04 Drug Resistance (GK) Drug Discovery (TD)	06 P3 (Diagnostic Microbiology) (SA/GK)
5.		11 Immunization (SA) Vaccine trials (LR)	13 *
6.		18 Immunology & Infection (SA)	20 P4 (Immunological Methods) (KT/VC)
	*Recess Week: Sat 21 Feb – Sun 1 Mar 2009 (1 week)*
7.	Mar	04 Opportunistic Infections (KT)	06 P5 (Molecular Techniques) (KT)
8.		11 New and ‘New’ Infections (KT)	13 P6 (Molecular Techniques) (KT)
9.		18 Team Presentations (VC/KT)	20 P7 (Molecular Techniques) (KT)
10.		25 Team Presentations (SA/SP)	27 *
11.	Apr	01 Team Presentations (SA/KP)	03 *
12.		08 Team Presentations (GS/LR)	10 *Good Friday*
13.		15 *	17 *
	READING WEEK : Sat 18 Apr to Fri 24Apr 2009 (1 week)
	EXAMINATION : Wed 29 April 2009 (9:00 am)
	VACATION : Sun 10 May to Sun 2 Aug 2009 (12 weeks)

Lecturers:

Dr Kevin SW Tan Lectures: 16 hrs

Dr Gamini Kumarasinghe Practicals / Tutorials: 26 hrs

Dr Sylvie Alonso Team Presentations: 8 hrs

Prof Sven Petterson (Guest Lecturer)

A/Prof Laurent Renia (Guest Lecturer)

Dr. Kevin Pethe (Guest Lecturer)

Dr. Thierry Diagana (Guest Lecturer)

Dr. Georges Snounou (Guest Lecturer)

Syllabus

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Text Book:

· Fundamentals of Microbiology, 8^th edition, Alcamo (Jones & Bartlett).

· Jawetz, Melnick & Adelberg's Medical Microbiology, 24^th edition, Lange Medical Books.

· Medical Microbiology, 4th edition, Baron S (Editor), University of Texas Medical Branch

Available free on-line (http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mmed)

Reference texts:

· Bacterial Pathogenesis: A Molecular Approach, 2nd edition, Salyers AA & Whitt DD, ASM Press.

· Infectious Disease, 2nd edition, Bannister BA, Begg NT & Gillespie SH, Blackwell Science.

Assessment

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MODE OF ASSESSMENT:

Oral (Team Presentation)	10%
Practical	10%
Written Report	20%
Final Examination	60%

Team Presentation (Oral):

Groups comprising 7-8 students per topic.

30 minutes presentation and 10 minutes Q & A. Total 40 minutes. Maximum of 3 persons per group involved in giving presentation.
Timing must be strictly adhered to. A timekeeper will be appointed. Your response to questions will be important in deciding marks given.
Maximum of 40 PowerPoint slides.
Each team is welcome to arrange for an informal meeting with designated lecturers to briefly discuss the topic.

Written report must be within the following parameters:

8 pages (including references)
A4 paper
Single side
12 point typeface
Double spacing
10 references

Diagram/s as you see fit.

Include title and name at the top of the first sheet.

Reports are to be handed up at the Microbiology General Office (MD4 Level 3) by Wednesday 15^th April 2009.

Workload

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